BAP1-TPDS is inherited in an autosomal dominant manner, which means that each child of an affected person has a 50% risk to inherit the condition. However, it appears that not…
Currently no clinical criteria have been established for the diagnosis of BAP1-TPDS. However the syndrome should be suspected and testing offered to individuals who have one of the following:
≥2…
There are several ways in which to manage the BAP1-TPDS:
Treatment of manifestations: For the most part, treatments for BAP1-TPDS tumors are the same as those used in standard practice…
The diagnosis of BAP1-TPDSis only made by identification of a mutation in BAP1 through genetic testing (usually done on a blood or saliva sample). Identification of a BAP1 mutation in…
The BAP1-TPDS is a hereditary cancer syndrome caused by mutations (also called pathogenic variants) in the BAP1 gene. It predisposes patients to a variety of cancers and a specific precancerous…